📘 Physical Chemistry – Overview
Physical Chemistry is one of the core subjects tested in both GPAT and NIPER JEE. It deals with the principles of chemistry and physics applied to pharmaceutical sciences, helping in understanding drug behavior, formulation stability, and molecular interactions.
In GPAT, Physical Chemistry appears under Other Subjects, contributing around 5–8 questions (20–32 marks).
In NIPER JEE, Physical Chemistry holds slightly higher weightage, with numericals and application-based MCQs commonly asked.
📂 Syllabus for Physical Chemistry (GPAT & NIPER 2025)
🔹 1. Thermodynamics
- Laws of Thermodynamics
- Work, Heat, Internal Energy, Enthalpy
- Entropy & Spontaneity
- Gibbs Free Energy, Helmholtz Free Energy
🔹 2. Chemical Kinetics
- Rate laws, Order & Molecularity
- Integrated Rate Equations
- Arrhenius Equation, Activation Energy
- Catalysis, Enzyme Kinetics
🔹 3. Ionic Equilibria
- Strong & Weak Electrolytes
- pH, Buffers, Solubility Product
- Hydrolysis of Salts
- Applications in Pharmaceutical formulations
🔹 4. Solutions & Colligative Properties
- Raoult’s Law, Osmotic Pressure
- Depression in Freezing Point, Elevation of Boiling Point
- Vapor Pressure lowering
- Molecular Weight Determination
🔹 5. Electrochemistry
- Galvanic & Electrolytic Cells
- Nernst Equation & Applications
- Electrode Potential
- Conductometry & Potentiometry (Pharmaceutical Analysis link)
🔹 6. Molecular Structure & Spectroscopy
- Quantum Chemistry basics
- Atomic & Molecular Orbitals
- UV-Vis, IR basics for structure determination
📖 Recommended Books for GPAT & NIPER
- Atkins’ Physical Chemistry – For theory & problem-solving
- Puri, Sharma & Pathania – Physical Chemistry – Standard reference for fundamentals
- Martin’s Physical Pharmacy – Application-based (very useful for NIPER)
- GPAT/NIPER Guides (Pearson / Arihant / Aggarwal) – For MCQ practice
🎯 Preparation Tips
- ✅ Make a formula sheet (Thermodynamics, Kinetics, Nernst, Arrhenius).
- ✅ Solve numerical problems daily (NIPER asks tricky numericals).
- ✅ For GPAT → focus on conceptual + applied MCQs.
- ✅ For NIPER → prepare problem-solving + advanced numericals.
- ✅ Revise buffer systems & colligative properties with pharma applications (like isotonicity).
📊 Weightage in Exams
- GPAT: 5–8 Questions (approx. 20–32 marks).
- NIPER JEE: 8–12 Questions (approx. 25–40 marks, including numerical).
📌 Conclusion
Physical Chemistry is a high-yield subject for both GPAT and NIPER JEE. While GPAT focuses on basic conceptual questions, NIPER requires a deeper problem-solving approach. By combining standard textbooks with MCQ practice, aspirants can strengthen this section and significantly improve their exam scores.